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Multi Sample Comparison for LCMS Data on LC Image HRMS Edition

Posted: November 13th, 2017, 5:07 am
by wenlzhan
Hi All,

I would like to enquire if we can perform multi sample comparison based on either TIC or EIC for LC/QTOF data in LC Image? Can cross sample feature matching be used to align TIC from multiple MS data files?

Thanks and Regards,
Wenlin

Re: Multi Sample Comparison for LCMS Data on LC Image HRMS Edition

Posted: November 13th, 2017, 10:09 am
by qtao
The Investigator program can be used to perform multiple sample comparison. Here is an overview of the Investigator workflow:
http://www.gcimage.com/publications/TCM ... lomics.pdf

Automated feature extraction is based on TIC, and the feature alignment is peak-based. The feature template generated can be used to align raw ms data through Register Images.