Multi Sample Comparison for LCMS Data on LC Image HRMS Edition

Ask or learn about how to use the software or troubleshoot problems
Post Reply
wenlzhan
Posts: 1
Joined: September 1st, 2015, 3:35 am

Multi Sample Comparison for LCMS Data on LC Image HRMS Edition

Post by wenlzhan » November 13th, 2017, 5:07 am

Hi All,

I would like to enquire if we can perform multi sample comparison based on either TIC or EIC for LC/QTOF data in LC Image? Can cross sample feature matching be used to align TIC from multiple MS data files?

Thanks and Regards,
Wenlin

qtao
Posts: 104
Joined: October 7th, 2011, 10:16 am

Re: Multi Sample Comparison for LCMS Data on LC Image HRMS Edition

Post by qtao » November 13th, 2017, 10:09 am

The Investigator program can be used to perform multiple sample comparison. Here is an overview of the Investigator workflow:
http://www.gcimage.com/publications/TCM ... lomics.pdf

Automated feature extraction is based on TIC, and the feature alignment is peak-based. The feature template generated can be used to align raw ms data through Register Images.

Post Reply